#chromothripsis

Unmasking Cancer's Architect of Chaos: N4BP2 Enzyme Drives DNA Rewiring and Drug Resistance

A groundbreaking discovery has revealed the N4BP2 enzyme as a key driver behind cancer's chaotic DNA rewiring, a process known as chromothripsis. This insight, published on ScienceDaily, offers a new understanding of how tumors rapidly evolve and resist therapies, potentially unlocking novel treatment strategies for aggressive cancers.